Buy the Yamaha AG06MK2 for a two-person podcast or a solo show with remote guests. Two phantom-powered inputs, a loopback switch and USB bus power cover most home podcasts, and at $239.99, or $203.99 on a good week, it costs less than most four-channel options. Budget for a headphone splitter, since it has one headphone jack.
The MAONO E2 Gen2 at $129.99 is the right start if you want sound pads, a mute button and battery power for phone recording, and can live with stereo-only USB and some uncertainty over the second input's phantom power.
The TASCAM Mixcast 4 earns its $499 the moment a third person sits down or call-ins become weekly: four inputs, four headphone outs, one USB track per mic and SD backup. If you stream on Windows alone with one mic, the TC Helicon GoXLR Mini at $189 is built for that, though it has no macOS support. For an in-room group without multitrack needs, the Behringer Xenyx X1204USB at $239 offers four mic preamps over stereo USB. Prices are mid1's weekly tracked prices; specs are the manufacturers'. mid1 does not test products.